Sorry if you are depressed, and I hope that you find your answers if that's what matters to you. To answer your question, no, I don't struggle with that. I have more important things to do in my life than wasting it looking for its "meaning".
Hi scratchme1010, I have some dark periods, but wouldn't describe myself as depressed. Definitely had severe depression in my early 20's but managed to deal with it through self help, supplements and the occasional medical treatment (didn't last last since I hated the side effects). Nowadays it's more like Winter blues, and I know how to stop myself brooding on thoughts that lead to the darkest places.
Partly I get down when I feel confused because I like to think I've got all the answers lol. Constantly thinking about life. Like to be in control, and am a natural problem solver. However, like I said, mostly I've become imbalanced from working too much (not left time for rest/leisure/socialisation) - and that's the biggest cause for feeling empty. When you're having fun with friends etc you just don't care so much about these questions; it just feels right.
Some have said in here that they don't have time/mental space for pondering life's meaning - I just don't get that. Obviously it's healthy to have enough activities/friends to distract you, but I can't see how this question isn't somewhat important as surely it shapes how you live your life now? Otherwise we're just "existing" (trying to survive like an animal) and that's it?
Admittedly, this same line of reasoning is a bit like "who created God" when a religionists says life couldn't have created itself. If I were to say that "surely life has an ultimate purpose/goal", then one could say but what makes that goal meaningful? And the circular nature goes on until one has to just say "it is what it is". All I can say is that there is truth in the whole "more happiness in giving than receiving", and at least for me that's one step ahead of "just existing" (doing what you can to survive).